Antimicrobial ciclopiroxolamine/clay nanocomposites
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989100%3A27640%2F18%3A10240007" target="_blank" >RIV/61989100:27640/18:10240007 - isvavai.cz</a>
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S2214785318309441" target="_blank" >https://www.sciencedirect.com/science/article/pii/S2214785318309441</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.matpr.2018.05.053" target="_blank" >10.1016/j.matpr.2018.05.053</a>
Alternative languages
Result language
angličtina
Original language name
Antimicrobial ciclopiroxolamine/clay nanocomposites
Original language description
The clay minerals are commonly used materials in pharmaceutical field both as inorganic excipients or active agents. We focused on the development of long-acting antimicrobial formula where clay minerals act as inorganic antimicrobial drug carries. Two series of organoclay nanocomposites with increasing amount of active antifungal drug ciclopiroxolamine were successfully synthesized through the intercalation reaction. In the first case clay mineral vermiculite was used as supporting matrix and secondly clay mineral bentonite was used. The structural characteristics of all prepared samples were studied by XRD and FTIR techniques. Furthermore, the content of organic carbon was determined for nanocomposite samples. Antimicrobial activity of nanocomposites was tested against bacterial strains Staphylococcus aureus and Escherichia coli, and against yeast Candida albicans and it was evaluated by finding minimum inhibitory concentration (MIC). Generally, nanocomposites based on clay mineral bentonite possess better antimicrobial activity.
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
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OECD FORD branch
20505 - Composites (including laminates, reinforced plastics, cermets, combined natural and synthetic fibre fabrics; filled composites)
Result continuities
Project
<a href="/en/project/ED1.1.00%2F02.0070" target="_blank" >ED1.1.00/02.0070: IT4Innovations Centre of Excellence</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
Materials Today: Proceedings. Volume 5, Supplement 1
ISBN
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ISSN
2214-7853
e-ISSN
2214-7853
Number of pages
9
Pages from-to
"S20"-"S28"
Publisher name
Elsevier
Place of publication
Amsterdam
Event location
Ostrava
Event date
May 22, 2017
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
000482182400004