Advances in bioink-based 3D printed scaffolds: optimizing biocompatibility and mechanical properties for bone regeneration
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989100%3A27730%2F25%3A10257546" target="_blank" >RIV/61989100:27730/25:10257546 - isvavai.cz</a>
Result on the web
<a href="https://pubs.rsc.org/en/content/articlelanding/2025/bm/d4bm01606h" target="_blank" >https://pubs.rsc.org/en/content/articlelanding/2025/bm/d4bm01606h</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1039/d4bm01606h" target="_blank" >10.1039/d4bm01606h</a>
Alternative languages
Result language
angličtina
Original language name
Advances in bioink-based 3D printed scaffolds: optimizing biocompatibility and mechanical properties for bone regeneration
Original language description
The development of bioink-based 3D-printed scaffolds has revolutionized bone tissue engineering (BTE) by enabling patient-specific and biomimetic constructs for bone regeneration. This review focuses on the biocompatibility and mechanical properties essential for scaffold performance, highlighting advancements in bioink formulations, material combinations, and printing techniques. The key biomaterials, including natural polymers (gelatin, collagen, alginate), synthetic polymers (polycaprolactone, polyethylene glycol), and bioactive ceramics (hydroxyapatite, calcium phosphate), are discussed concerning their osteoconductivity, printability, and structural integrity. Despite significant progress, challenges remain in achieving optimal mechanical strength, degradation rates, and cellular interactions. The review explores emerging strategies such as gene-activated bioinks, nanocomposite reinforcements, and crosslinking techniques to enhance scaffold durability and bioactivity. By synthesizing recent developments, this work provides insights into future directions for bioink-based scaffolds, paving the way for more effective and personalized bone regenerative therapies.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
20500 - Materials engineering
Result continuities
Project
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Continuities
O - Projekt operacniho programu
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Biomaterials Science
ISSN
2047-4830
e-ISSN
2047-4849
Volume of the periodical
2025
Issue of the periodical within the volume
07 Apr 2025
Country of publishing house
GB - UNITED KINGDOM
Number of pages
24
Pages from-to
35
UT code for WoS article
001460256000001
EID of the result in the Scopus database
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