Minipig cytochrome P450 3A, 2A and 2C enzymes have similar properties to human analogs

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F01%3A00000444" target="_blank" >RIV/61989592:15110/01:00000444 - isvavai.cz</a>

Alternative codes found

RIV/61989592:15110/01:00000474 RIV/00023795:_____/01:00004797 RIV/61989592:15110/01:00006972

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Minipig cytochrome P450 3A, 2A and 2C enzymes have similar properties to human analogs

Original language description

Minipig cytochrome P450 3A, 2A and 2C enzymes have similar properties to human analogs. The purpose of this work is to characterize minipig liver microsomal cytochromes P450 (CYPs) by comparing their N-terminal sequences with corresponding humal orthologs. The results support the view that minipigs may serve as model animals in pharmacological studies with substrates of human CYP enzymes.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CE - Biochemistry

OECD FORD branch

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Project

<a href="/en/project/GA203%2F99%2F0277" target="_blank" >GA203/99/0277: Cytochrome P450 3A - key enzyme of drug metabolism. Comparison of the human enzyme and of the model system</a><br>

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2001

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

BMC Pharmacology

ISSN

1471-2210

e-ISSN

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Volume of the periodical

1

Issue of the periodical within the volume

11

Country of publishing house

GB - UNITED KINGDOM

Number of pages

1

Pages from-to

00-00

UT code for WoS article

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EID of the result in the Scopus database

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