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Immunohistochemical detection of the hMLH1 and hMSH2 proteins in hereditary non-polyposis colon cancer and sporadic colon cancer

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F04%3A00000926" target="_blank" >RIV/61989592:15110/04:00000926 - isvavai.cz</a>

  • Alternative codes found

    RIV/00209805:_____/04:00013900 RIV/00216208:11110/04:00009322 RIV/00064165:_____/04:00001124 RIV/00843989:_____/04:00011851

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Immunohistochemical detection of the hMLH1 and hMSH2 proteins in hereditary non-polyposis colon cancer and sporadic colon cancer

  • Original language description

    Defects in DNA mismatch repair system are involved in carcinogenesis of sporadic and inherited human cancers. We assessed the feasibility of using immunohistochemistry to detect tumors with DNA mismatch repair deficiency.

  • Czech name

    Immunohistochemical detection of the hMLH1 and hMSH2 proteins in hereditary non-polyposis colon cancer and sporadic colon cancer

  • Czech description

    Poruchy systému nápravy nesprávného spojení DNA se podílí na karcinogenezi nahodilých a dědičných rakovinových onemocnění člověka. Snahou je zjistit, zda je možné použít imunohistochemii k odhalení nádorového onemocnění při nedostatečnosti tohoto DNA nápravného systému. Studie potvrdila, že imunohistochemie proteinů hMLH1 a hMSHě je užitečnou metodou k předpovědi existence nedostatečnosti nápravného systému.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FD - Oncology and haematology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/NC6741" target="_blank" >NC6741: Clinical and pothogenetic aspects of telomerase activity in colorectal and breast cancer with respect to their sporadic versus hereditary occurence</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2004

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Neoplasma

  • ISSN

    0028-2685

  • e-ISSN

  • Volume of the periodical

    51

  • Issue of the periodical within the volume

    4

  • Country of publishing house

    SK - SLOVAKIA

  • Number of pages

    10

  • Pages from-to

    275-284

  • UT code for WoS article

  • EID of the result in the Scopus database