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Primary medistinal (thymic) larbe G-cell lymphom with a der(14)t(8;14)(q24;q32) and a translocation of MYC to the derivative chromosome 114 with a deleted IgH locus

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F06%3A00003189" target="_blank" >RIV/61989592:15110/06:00003189 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Primary medistinal (thymic) larbe G-cell lymphom with a der(14)t(8;14)(q24;q32) and a translocation of MYC to the derivative chromosome 114 with a deleted IgH locus

  • Original language description

    We report a case of primary mediastinal (thymic) large B-cell lymphoma (PMBL) with an inicital karyotype containing numerical chromosomal aberrations: +X, +9, +12, +21, and a novel translocation T)2;11)(q?31);q23-24) with a duplication of the derivativechromosome 11. Subsequent multicolor fluorescence in situ hybridization (M-FISH) analysis revealed a der (14)t(8;14)(q24;32).

  • Czech name

    Primární mediastinální velkobuněčný lymfom s (14)t(8;14)(q24;q32) a přenesení MYC na der(14) a ztrátou lokusu IgH

  • Czech description

    Kazuistika případu primárního mediastinálního velkobuněčného B-lymfomu s novou chromosomální translokací t(2;11)(q?31;q23-24). Pomocí FISH byla prokázána ztráta celého lokusu IgH z der(14)t(8;14) a přenesení MYC na der(14). Aktivace MYC způsobená jeho translokací může být významnou událostí v patogenezi tohoto onemocnění.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FD - Oncology and haematology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/NR9050" target="_blank" >NR9050: Contribution of cytogenetics, molecular cytogenetics and arrayCGH for the exact definition of genetic chages in selected pediatric solid tumors</a><br>

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2006

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Cancer Genetics and Cytogenetics

  • ISSN

    0165-4608

  • e-ISSN

  • Volume of the periodical

    170

  • Issue of the periodical within the volume

    2

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    5

  • Pages from-to

    158-162

  • UT code for WoS article

  • EID of the result in the Scopus database