Urinary neopterin, hemoglobin and peripheral blood cell counts in breast carcinoma patients treated with dose.dense chemotherapy.

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F08%3A00007573" target="_blank" >RIV/61989592:15110/08:00007573 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11160/08:00109167 RIV/00179906:_____/08:00001091 RIV/00216208:11150/08:00106742

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Urinary neopterin, hemoglobin and peripheral blood cell counts in breast carcinoma patients treated with dose.dense chemotherapy.

Original language description

Among other actions, chemotherapy may induce an activation of systemic inflammatory and immune response. Patients and Methods: Urinary neopterin was evaluated, using high-performance liquid chromatography, before and during dose-dense combination chemotherapy with doxorubicin, cyclophosphamide and sequential paclitaxel (neoadjuvant or adjuvant) in 194 patients with breast carcinoma. Hemoglobin, peripheral blood cell count and, in a subgroup of patients, iron metabolism were also evaluated. Results: Urinary neopterin increased significantly during the chemotherapy. The increase in urinary neopterin was accompanied by a gradual decrease of hemoglobin. A marked increase in serum ferritin concentration was observed during the chemotherapy, along with fluctuations of iron concentrations. Among 161 patients treated with primary chemotherapy, the pathological response was evaluable in 150. Pathological complete response was observed in 37 cases (25%). In patients with pathological complete re

Czech name

Neopterin v moči stoupá během chemoterapie

Czech description

Neopterin v moči stoupá během chemoterapie

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FD - Oncology and haematology

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2008

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Anticancer Research

ISSN

0250-7005

e-ISSN

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Volume of the periodical

28

Issue of the periodical within the volume

1

Country of publishing house

GR - GREECE

Number of pages

8

Pages from-to

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UT code for WoS article

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EID of the result in the Scopus database

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