Improvement of cardiovascular risk factors and cosmetic side effects in kidney transplant recipients after conversion to tacrolimus

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F09%3A00009787" target="_blank" >RIV/61989592:15110/09:00009787 - isvavai.cz</a>

Result on the web

—

DOI - Digital Object Identifier

—

Result language

angličtina

Original language name

Improvement of cardiovascular risk factors and cosmetic side effects in kidney transplant recipients after conversion to tacrolimus

Original language description

Aims: Tacrolimus and cyclosporine A (CyA) are cornerstones in immunosuppressive therapy. Cyclosporine side effects include hypertension and hypercholesterolemia both of which may increase the risk of cardiovascular mortality, gingival hyperplasia and hirsutism are known to reduce quality of life. The aim of this prespective study was to evaluate changes in cardiovascular risk profile and cosmetic side effects after conversion from CyA to tacrolimus. Methods: 25 stable kidney transplant recipients (9 male, 16 female) were converted froma a CyA to a tacrolimus - based regimen. Mean age was 45,7 +- 13,5 years. Time to switch following transplantation was 4,8+-1,7 years. Resons for conversion were multiple: arterial hypertension (9), hypertrichosis (3), gingival hyperplasia (3), hyperlipidemia (14). Results: 19/25 patients completed the one year study period. One patient died, two returned to hemodialysis. two were switched back to CyA and one patient was lost to follow-up. there were stat

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FE - Other fields of internal medicine

OECD FORD branch

—

Project

<a href="/en/project/NS9964" target="_blank" >NS9964: Oxidative stress and antioxidative mechanisms after kidney transplantation</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2009

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Biomedical Papers

ISSN

1213-8118

e-ISSN

—

Volume of the periodical

153

Issue of the periodical within the volume

1

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

8

Pages from-to

—

UT code for WoS article

—

EID of the result in the Scopus database

—