Cystic fibrosis fatty acid imbalance is linked to ceramide deficiency and corrected by fenretinide
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F09%3A10214127" target="_blank" >RIV/61989592:15110/09:10214127 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Cystic fibrosis fatty acid imbalance is linked to ceramide deficiency and corrected by fenretinide
Original language description
Cystic fibrosis (CF) patients and CFTR knock-out mice (CF mice) display an imbalance in fatty acids with high arachidonic acid (AA) and low docosahexaenoic acid (DHA) concentrations. Our recent studies demonstrated defects in another class of lipids, ceramides, in CF patients and CF mice. This study investigates the relationship between ceramide, AA, DHA and the correction of lipid imbalances in CF mice following treatment with fenretinide.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Result continuities
Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2009
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
American Journal of Respiratory Cell and Molecular Biology
ISSN
1044-1549
e-ISSN
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Volume of the periodical
41
Issue of the periodical within the volume
1
Country of publishing house
US - UNITED STATES
Number of pages
7
Pages from-to
100-106
UT code for WoS article
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EID of the result in the Scopus database
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