HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F10%3A10215634" target="_blank" >RIV/61989592:15110/10:10215634 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1038/ncb2008" target="_blank" >http://dx.doi.org/10.1038/ncb2008</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1038/ncb2008" target="_blank" >10.1038/ncb2008</a>
Alternative languages
Result language
angličtina
Original language name
HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes
Original language description
Regulatory ubiquitylation is emerging as an important mechanism to protect genome integrity in cells exposed to DNA damage1-9. However, the spectrum of known ubiquitin regulators of the DNA damage response (DDR) is limited and their functional interplayis poorly understood. Here, we identify ERC2 as a factor that regulates ubiquitin-dependent retention of repair proteins on damaged chromosomes.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FP - Other medical fields
OECD FORD branch
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Result continuities
Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Nature Cell Biology (print)
ISSN
1465-7392
e-ISSN
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Volume of the periodical
12
Issue of the periodical within the volume
1
Country of publishing house
GB - UNITED KINGDOM
Number of pages
19
Pages from-to
80-98
UT code for WoS article
000272973800016
EID of the result in the Scopus database
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