Genetic testing for pheochromocytoma
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F10%3A10224193" target="_blank" >RIV/61989592:15110/10:10224193 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Genetic testing for pheochromocytoma
Original language description
According to latest discoveries about 30% of pheochromocytomas and paragangliomas have identified being of inherited origin. Germline mutations used to be found in 100% of syndromic cases and about 90% of patients with positive familial history. In non-syndromic patients with apparently sporadic tumor the frequency of genetic mutations varies between 7.5-27%. Nowadays, genetic testing is recommended for all patients with pheochromocytoma or paraganglioma. The proper order of tested genes could be basedon histological evaluation, localization and biochemical phenotype of the present tumor. Identification of gene mutation may also lead to early diagnosis, treatment, regular surveillance and better prognosis in other family members.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FB - Endocrinology, diabetology, metabolism, nutrition
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Current Hypertension Reviews
ISSN
1573-4021
e-ISSN
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Volume of the periodical
12
Issue of the periodical within the volume
6
Country of publishing house
US - UNITED STATES
Number of pages
9
Pages from-to
456-464
UT code for WoS article
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EID of the result in the Scopus database
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