Formation of AR-SMRT binding in prostate cancer cells treated with natural histone deacetylase inhibitor

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F10%3A33140357" target="_blank" >RIV/61989592:15110/10:33140357 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.3233/CBM-2010-0150" target="_blank" >http://dx.doi.org/10.3233/CBM-2010-0150</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3233/CBM-2010-0150" target="_blank" >10.3233/CBM-2010-0150</a>

Result language
angličtina
Original language name
Formation of AR-SMRT binding in prostate cancer cells treated with natural histone deacetylase inhibitor
Original language description
Signaling through the androgen receptor (AR) plays a critical role in prostate cancer progression. The AR is a classical nuclear receptor (NR) providing a link between signaling molecule and transcription response. Histone deacetylase inhibitors (HDACI)have antiproliferative and proapoptotic effects on prostate cancer cells and their implication in silence AR signaling may have potential therapeutic use.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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