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Microbial challenge tests on nonradioactive TiO2-based 68Ge/68Ga generator columns

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F12%3A33140503" target="_blank" >RIV/61989592:15110/12:33140503 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1097/MNM.0b013e3283543323" target="_blank" >http://dx.doi.org/10.1097/MNM.0b013e3283543323</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1097/MNM.0b013e3283543323" target="_blank" >10.1097/MNM.0b013e3283543323</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Microbial challenge tests on nonradioactive TiO2-based 68Ge/68Ga generator columns

  • Original language description

    Objectives The aim of this study was to test the survival of microorganisms in eluents used for Ge-68/Ga-68 generators and for regeneration of nonradioactive Ge-68/Ga-68 generator columns after high microbial load. Nonradioactive generator columns were loaded with various microorganisms and tested to determine whether the microorganisms were proliferating or surviving in eluates of the columns. Materials and methods TiO2 columns used in a commercially available Ge-68/Ga-68 generators for absorption of Ge-68 were loaded with greater than 10(7) colony-forming units (CFU) of Staphylococcus aureus, Clostridium sporogenes, Candida albicans, Helicobacter pylori, Aspergillus niger and Deinococcus radiodurans. Columns were eluted with 0.1 N HCl under standardeluting conditions. Elutions, over a prolonged time period, were tested for endotoxins, sterility and number of CFU. Results Initial tests on the eluent (0.1 N HCl) already showed limited survival of microorganisms. Using TiO2 generator c

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FD - Oncology and haematology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/ED0030%2F01%2F01" target="_blank" >ED0030/01/01: Biomedicine for regional development and human resources</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2012

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Nuclear Medicine Communications

  • ISSN

    0143-3636

  • e-ISSN

  • Volume of the periodical

    33

  • Issue of the periodical within the volume

    8

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    5

  • Pages from-to

    819-823

  • UT code for WoS article

    000306584300004

  • EID of the result in the Scopus database