Prior Use of Antiplatelet Therapy Can Be Associated with a Higher Chance for Early Recanalization of the Occluded Middle Cerebral Artery in Acute Stroke Patients Treated with Intravenous Thrombolysis

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F12%3A33140541" target="_blank" >RIV/61989592:15110/12:33140541 - isvavai.cz</a>

Alternative codes found

RIV/00098892:_____/12:#0000391 RIV/00843989:_____/12:00102129

Result on the web

<a href="http://dx.doi.org/10.1159/000333064" target="_blank" >http://dx.doi.org/10.1159/000333064</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1159/000333064" target="_blank" >10.1159/000333064</a>

Result language

angličtina

Original language name

Prior Use of Antiplatelet Therapy Can Be Associated with a Higher Chance for Early Recanalization of the Occluded Middle Cerebral Artery in Acute Stroke Patients Treated with Intravenous Thrombolysis

Original language description

Background:The early recanalization (ER) of an occluded cerebral artery is important for clinical improvement in acute ischemic stroke. The aim of the study was to assess the possible association between the prior use of antiplatelets (AP) and ER of occluded middle cerebral artery (MCA) after intravenous thrombolysis (IVT).Results: Fifty-six patients (28 males, mean age: 69.8 +/- 9.8 years) used AP and 90 patients were AP naive (51 males, mean age: 65.8 +/- 12.5 years). Prior AP use was associated witha higher rate of early MCA recanalization (53.6 vs. 29.5% in AP naive, p = 0.007) and was shown as a predictor of ER (OR: 2.30, 95% CI: 1.14-4.65; p = 0.020) in unadjusted analysis. No difference was found in the occurrence of SICH. Conclusion: Prior useof AP was associated with a higher rate of ER of occluded MCA, but with no increase of SICH after IVT.

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FH - Neurology, neuro-surgery, nuero-sciences

OECD FORD branch

—

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

European Neurology

ISSN

0014-3022

e-ISSN

—

Volume of the periodical

67

Issue of the periodical within the volume

1

Country of publishing house

CH - SWITZERLAND

Number of pages

5

Pages from-to

52-56

UT code for WoS article

000299719000010

EID of the result in the Scopus database

—