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The safety and efficacy of bridging full-dose IV-IA thrombolysis in acute ischemic stroke patients with MCA occlusion: A comparison with IV thrombolysis alone

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F14%3A33150063" target="_blank" >RIV/61989592:15110/14:33150063 - isvavai.cz</a>

  • Alternative codes found

    RIV/00098892:_____/14:#0000709

  • Result on the web

    <a href="http://dx.doi.org/10.5507/bp.2013.003" target="_blank" >http://dx.doi.org/10.5507/bp.2013.003</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.5507/bp.2013.003" target="_blank" >10.5507/bp.2013.003</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    The safety and efficacy of bridging full-dose IV-IA thrombolysis in acute ischemic stroke patients with MCA occlusion: A comparison with IV thrombolysis alone

  • Original language description

    Aims. Early recanalization of the occluded cerebral artery is substantial for clinical improvement in acute ischemic stroke (IS) patients. The rate of achieved recanalizations using IVT is low. The aim of this study was to compare the safety and efficacyof bridging full-dose intravenous-intraarterial (IV-IA) thrombolysis to IVT alone in acute IS patients with occluded MCA. Methods. Seventy-nine consecutive IS patients with MCA occlusion were treated either with IVT alone (historic controls, Group 1) orwith full-dose IV-IA thrombolysis (Group 2). Stroke severity was evaluated using NIHSS, achieved recanalizations using transcranial Doppler (Group 1) or angiography (Group 2). Occurrence of ICH including SICH was evaluated after 24 hours. 90-day clinical outcome was evaluated using modified Rankin Scale (mRS). Results. Group 1 consisted of 50 patients (24 males, mean age 70.8 +- 10.2 years) and Group 2 of 29 patients (14 males, mean age 67.8 +- 10.0 years). No difference was found in th

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FH - Neurology, neuro-surgery, nuero-sciences

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2014

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Biomedical Papers-Olomouc

  • ISSN

    1213-8118

  • e-ISSN

  • Volume of the periodical

    158

  • Issue of the periodical within the volume

    3

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    6

  • Pages from-to

    391-396

  • UT code for WoS article

  • EID of the result in the Scopus database