High expression of the RNA-binding protein RBPMS1 in gastrointestinal stromal tumors

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F13%3A33144974" target="_blank" >RIV/61989592:15110/13:33144974 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.yexmp.2012.12.004" target="_blank" >http://dx.doi.org/10.1016/j.yexmp.2012.12.004</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.yexmp.2012.12.004" target="_blank" >10.1016/j.yexmp.2012.12.004</a>

Result language
angličtina
Original language name
High expression of the RNA-binding protein RBPMS1 in gastrointestinal stromal tumors
Original language description
Gastrointestinal stroma tumors (GISTs) are the most common mesenchymal neoplasms of the gastrointestinal tract and are oftern associated with KIT or PDGFRA gene mutations. GIST cells might arise from the interstitial cells of Cajal (ICCs) or from a mesenchymal precursor that is common to ICCs and smooth muscle cells (SMCs). Here, we analyzed the mRNA and protein expression of RNA-Binding Protein with Multiple Splicing-2 (RBPMS2), an early marker of gastrointestinal SMC precursors, in human GISTs (n=23)by in situ hybridization, quantitative RT-PCR analysis and immunohistochemistry.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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