Determination of isoquinoline alkaloids in different feeds and animal tissues. Toxicity of Argemone mexicana seeds and dihydrosanguinarine in Wistar rat

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F13%3A33147681" target="_blank" >RIV/61989592:15110/13:33147681 - isvavai.cz</a>

Result on the web

<a href="http://Uložen" target="_blank" >http://Uložen</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Determination of isoquinoline alkaloids in different feeds and animal tissues. Toxicity of Argemone mexicana seeds and dihydrosanguinarine in Wistar rat

Original language description

The extraction process and LC-MS method The LC-MS for determination of isoquinoline alkaloids in biological matrix were elaborated. The effect of seeds on rat health status was evaluated in a 25 days experiment involving consumption of feed containing 0.5 % (w/w), 1 % or 1 % solar irradiated seeds of A. mexicana or dihydrosanguinarine equal to its amount in 1 % seeds in diet. The following parameters were monitored: body and organ weights; hematology markers in blood; safety clinical laboratory and oxidative stress markers in plasma and erythrocytes, and histological examination of small intestine and liver.

Czech name

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Czech description

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Type

V_souhrn - Summary research report

CEP classification

CE - Biochemistry

OECD FORD branch

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Project

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Continuities

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Publication year

2013

Confidentiality

C - Předmět řešení projektu podléhá obchodnímu tajemství (§ 504 Občanského zákoníku), ale název projektu, cíle projektu a u ukončeného nebo zastaveného projektu zhodnocení výsledku řešení projektu (údaje P03, P04, P15, P19, P29, PN8) dodané do CEP, jsou upraveny tak, aby byly zveřejnitelné.

Number of pages

7

Place of publication

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Publisher/client name

PHYTOBIOTICS Futterzusatzstoffe GmbH, Wallufer Str. 10a, D-65343, Germany

Version

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