Prognostic Significance of CD3 Tumor-infiltrating Lymphocytes in Patients with Endometrial Carcinoma
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F14%3A33150509" target="_blank" >RIV/61989592:15110/14:33150509 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11150/14:10283483 RIV/00179906:_____/14:10283483
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Prognostic Significance of CD3 Tumor-infiltrating Lymphocytes in Patients with Endometrial Carcinoma
Original language description
Aim: The aim of the present study was to investigate tumor-infiltrating leukocytes in patients with endometrial carcinoma. Patients and Methods: Cluster of differentiation (CD) 3(+), CD8(+) and C20(+) tumor-infiltrating lymphocytes (TILs) and CD68(+) tumor-associated macrophages (TAMs) were evaluated retrospectively by immunohistochemistry in tumor specimen from 124 patients with endometrial carcinoma. Results: A significant decrease of CD3(+) TILs and an increase of CD68(+) TAM count was associated with higher tumor stage. In patients with earlystage, high-risk tumors, low intraepithelial CD3(+) TIL counts were associated with significantly inferior survival. In multivariate analysis of patients with early-stage tumors, intraepithelial CD3(+) TIL counts were an independent predictor of survival. Conclusion: In patients with endometrial carcinoma a decrease of intraepithelial CD3(+) TIL counts is associated with advanced stage and high risk group. Intraepithelial CD3(+) TIL counts are
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Anticancer Research
ISSN
0250-7005
e-ISSN
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Volume of the periodical
34
Issue of the periodical within the volume
10
Country of publishing house
GR - GREECE
Number of pages
7
Pages from-to
5555-5561
UT code for WoS article
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EID of the result in the Scopus database
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