Detection of minimal residual disease in lung cancer

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F14%3A33150537" target="_blank" >RIV/61989592:15110/14:33150537 - isvavai.cz</a>
Alternative codes found
RIV/00098892:_____/14:#0000751
Result on the web
<a href="http://biomed.papers.upol.cz/artkey/bio-201402-0005_Detection_of_minimal_residual_disease_in_lung_cancer.php?back=%2Fsearch.php%3Fquery%3DChudacek%26sfrom%3D0%26spage%3D30" target="_blank" >http://biomed.papers.upol.cz/artkey/bio-201402-0005_Detection_of_minimal_residual_disease_in_lung_cancer.php?back=%2Fsearch.php%3Fquery%3DChudacek%26sfrom%3D0%26spage%3D30</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.5507/bp.2013.019" target="_blank" >10.5507/bp.2013.019</a>

Result language
angličtina
Original language name
Detection of minimal residual disease in lung cancer
Original language description
Background. Even after successful radical treatment of lung cancer, patients in stages I and II frequently suffer recurrence, which end lethally. Detection of subclinical residual disease after surgery is thus one of the most important emerging diagnostic methods. Minimal residual disease (MRD) is defined as the presence of isolated tumor cells or circulating cells in a patient after curative primary tumor removal and at the same time, no clinical signs of cancer. Conventional methods cannot detect MRDand hence there is a need for new molecular biological methods. Methods. We searched the PubMed database for original and review articles on MRD in lung cancer. Search words were "lung cancer", "minimal residual disease" and "detection of minimal residual disease". The publications we found were compared with the results of our own studies on the detection of MRD in lung cancer and the personal experiences are described. Examination of blood samples from 98 healthy volunteers and bone ma
Czech name
—
Czech description
—

Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FJ - Surgery including transplantology
OECD FORD branch
—

Project
<a href="/en/project/NT14406" target="_blank" >NT14406: Monitoring the effect of lung cancer treatment using quantitative analysis of gene expression of minimal residual disease biomarkers</a><br>
Continuities
S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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