Determination of adipokine expression in the peripheral blood leukocytes of young patients with myocardial infarction
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F14%3A33151444" target="_blank" >RIV/61989592:15110/14:33151444 - isvavai.cz</a>
Alternative codes found
RIV/00098892:_____/14:#0000780
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Determination of adipokine expression in the peripheral blood leukocytes of young patients with myocardial infarction
Original language description
Objectives: Little is known about the effect of adipokines in the pathogenesis of the acute myocardial infarction (AMI) in young patients. The aim of this pilot study was to evaluate whether it is possible to detect mRNA expressions of selected adipokines in the peripheral blood leukocytes of young patients with myocardial infarction. Methods: We prospectively examined 42 patients who had an acute myocardial infarction (AMI) at a young age (men 18-45 years of age and women 18-55 years of age) and control groups of 31 patients with metabolic syndrome and 15 healthy individuals. RNA was isolated from their peripheral blood leukocytes and transcribed into cDNA (transcription kit iSCRIPT). Subsequently, the expression of the following genes were analysed (LC 480II, BioVendor kits): Adipocyte Fatty Acid Binding protein (AFABP, FABP4), Leptin and Adiponectin receptor 2 (ADN-R2). Beta-2-microglobulin was examined as a housekeeping gene. Results: In the group of patients after AMI the expressi
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FA - Cardiovascular diseases including cardio-surgery
OECD FORD branch
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Result continuities
Project
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Continuities
O - Projekt operacniho programu
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Experimental and Clinical Cardiology
ISSN
1205-6626
e-ISSN
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Volume of the periodical
20
Issue of the periodical within the volume
1
Country of publishing house
CH - SWITZERLAND
Number of pages
13
Pages from-to
1182-1194
UT code for WoS article
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EID of the result in the Scopus database
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