IL28B genotyping and treatment of HCV infected subjects

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F14%3A33152198" target="_blank" >RIV/61989592:15110/14:33152198 - isvavai.cz</a>

Alternative codes found

RIV/00098892:_____/14:#0000811

Result on the web

<a href="http://dx.doi.org/10.5372/1905-7415.0804.313" target="_blank" >http://dx.doi.org/10.5372/1905-7415.0804.313</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.5372/1905-7415.0804.313" target="_blank" >10.5372/1905-7415.0804.313</a>

Result language

angličtina

Original language name

IL28B genotyping and treatment of HCV infected subjects

Original language description

Background: Chronic hepatitis C is a common cause of advanced liver disease and appropriate treatment has been complex and a challenge. Reaction of individual genotypes to classical pegylated interferon-ribavirin therapy differs and no success has been achieved in some even after repeated therapy cycles. New types of so called directly acting antivirals (DAAs) are hopeful, as shown in many recent clinical studies, and triple therapy regimens involving DAA are becoming the new standard of care. Objective: To summarize knowledge about the relationship between HCV therapeutic regimens and the genetic background of the host represented by interleukin 28B (IL28B) gene polymorphisms. In the first part, the host basic mechanisms in specific and innate immunity are introduced. The IL28B genotype and its role in the course of HCV treatment are described in the second part. Methods: We searched and summarized publications on HCV therapeutic regimens and host IL28B polymorphisms. Results: Compare

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FP - Other medical fields

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Asian Biomedicine

ISSN

1905-7415

e-ISSN

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Volume of the periodical

8

Issue of the periodical within the volume

4

Country of publishing house

TH - THAILAND

Number of pages

8

Pages from-to

445-452

UT code for WoS article

000345883100002

EID of the result in the Scopus database

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