Dynamic changes in microRNA expression profiles reflect progression of Barrett's esophagus to esophageal adenocarcinoma

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F15%3A33154119" target="_blank" >RIV/61989592:15110/15:33154119 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14740/15:00080394 RIV/00209805:_____/15:#0000702

Result on the web

<a href="http://carcin.oxfordjournals.org/content/36/5/521.full.pdf+html" target="_blank" >http://carcin.oxfordjournals.org/content/36/5/521.full.pdf+html</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1093/carcin/bgv023" target="_blank" >10.1093/carcin/bgv023</a>

Result language

angličtina

Original language name

Dynamic changes in microRNA expression profiles reflect progression of Barrett's esophagus to esophageal adenocarcinoma

Original language description

We have described miRNAs progressively deregulated in sequential carcinogenesis EM-BE-EAC and identified miRNA signatures enabling classification of EM, BE and EAC samples with moderate accuracy indicating their potential for diagnostics and risk stratification.Esophageal adenocarcinoma (EAC) is highly aggressive malignancy that frequently develops from Barrett's esophagus (BE), a premalignant pathologic change occurring in the lower end of the esophagus. MicroRNAs (miRNAs) are small, non-coding RNAs that function as posttranscriptional regulators of gene expression and were repeatedly proved to play key roles in pathogenesis of BE as well as EAC.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FD - Oncology and haematology

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Carcinogenesis

ISSN

0143-3334

e-ISSN

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Volume of the periodical

36

Issue of the periodical within the volume

5

Country of publishing house

GB - UNITED KINGDOM

Number of pages

7

Pages from-to

521-527

UT code for WoS article

000354746400002

EID of the result in the Scopus database

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