All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”

Platelet-derived growth factor signaling in the lung. From lung development and disease to clinical studies

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F15%3A33154230" target="_blank" >RIV/61989592:15110/15:33154230 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1165/rcmb.2014-0294TR" target="_blank" >http://dx.doi.org/10.1165/rcmb.2014-0294TR</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1165/rcmb.2014-0294TR" target="_blank" >10.1165/rcmb.2014-0294TR</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Platelet-derived growth factor signaling in the lung. From lung development and disease to clinical studies

  • Original language description

    Platelet-derived growth factors (PDGFs) and their receptors (PDGFRs) represent one of the most intensively studied families of growth factors in the last four decades. PDGF signaling plays an essential role in cell proliferation, differentiation, migration, and survival. In vivo studies have documented an important role of PDGF signaling in the normal development of several organs, such as the kidney, eye, or lung. PDGF signaling is essential for the formation of intact mesenchymal cells during embryogenesis. Recently, this knowledge has been extended to a role of PDGF signaling in diseases in general, such as cancer and atherosclerosis, and more importantly in lung diseases, including pulmonary arterial hypertension, lung cancer, and lung fibrosis. Inthis review, we provide an up-to-date overview of PDGF signaling, including tissue- and cell-type-specific expression patterns and effects. We highlight current therapeutic approaches modifying PDGF signaling in lung diseases and summari

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EB - Genetics and molecular biology

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    American Journal of Respiratory, Cell and Molecular Biology (print)

  • ISSN

    1044-1549

  • e-ISSN

  • Volume of the periodical

    52

  • Issue of the periodical within the volume

    3

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    22

  • Pages from-to

    263-284

  • UT code for WoS article

    000352208100001

  • EID of the result in the Scopus database