Expression of VEGF-C/-D and lymphangiogenesis in salivary adenoid cystic carcinoma
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F15%3A33156003" target="_blank" >RIV/61989592:15110/15:33156003 - isvavai.cz</a>
Alternative codes found
RIV/00098892:_____/15:#0000953 RIV/00216208:11140/15:10315907
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Expression of VEGF-C/-D and lymphangiogenesis in salivary adenoid cystic carcinoma
Original language description
Aims: Some human neoplasms stimulate lymphangiogenesis through the over-production of vascular endothelial growth factors C/D (VEGF-C/D). Previously little attention has been paid to the mechanisms of lymphogenous spread of salivary adenoid cystic carcinoma (SACC). The current study investigates the presence of lymphatic network and the role of VEGF-C and VEGF-D in its formation. Methods: The retrospective study was performed in 20 (12 females and 8 males) patients diagnosed with SACC. For the evaluation of VEGF-C/D immunoreactivity, semiquantitative histoscore was calculated as a sum of positive tumor cell score (range 0 to 3) and staining intensity (range 0 to 3). Lymphatic vessel density (LVD) was determined as the number of D2-40 positive lymphaticcapillaries present at "hot spots". Moreover, the values of histoscores were calculated in surrounding normal parotid parenchyma and compared to those counted in tumors. LVD in the tumor center (iLVD), in its periphery (pLVD), and in hea
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FF - ENT (ie. ear, nose, throat), ophthalmology, dentistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/NT13701" target="_blank" >NT13701: Expression of vascular endothelial growth factor VEGF-C/D and its significance for lymphangioneogenesis, nodal metastase and prognosis of salivary gland carcinomas.</a><br>
Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Pathology Research and Practice
ISSN
0344-0338
e-ISSN
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Volume of the periodical
211
Issue of the periodical within the volume
10
Country of publishing house
DE - GERMANY
Number of pages
7
Pages from-to
759-765
UT code for WoS article
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EID of the result in the Scopus database
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