Analysis of thymidine kinase serum levels by novel method DiviTum TM in multiple myeloma and monoclonal gammopathy of undetermined significance - comparison with imaging methods 99mTc-MIBI scintigraphy and 18F-FDG PET/CT

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F15%3A33156469" target="_blank" >RIV/61989592:15110/15:33156469 - isvavai.cz</a>

Alternative codes found

RIV/00098892:_____/15:#0000874

Result on the web

<a href="http://dx.doi.org/10.5507/bp.2014.008" target="_blank" >http://dx.doi.org/10.5507/bp.2014.008</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.5507/bp.2014.008" target="_blank" >10.5507/bp.2014.008</a>

Result language

angličtina

Original language name

Analysis of thymidine kinase serum levels by novel method DiviTum TM in multiple myeloma and monoclonal gammopathy of undetermined significance - comparison with imaging methods 99mTc-MIBI scintigraphy and 18F-FDG PET/CT

Original language description

The study aimed at comparing two methods for evaluatiing thymidinekinase TK in serum - an older RIA method and novel DiviTum TM - in patients with MM and MGUS, and also comparing them with biochemical markers and degree of aktivity evaluated by imaging methods 99mTc-MIBI scintigraphy and 18F-FDG PET/CT. Analysis revealed a significant correlation between TK in serum and LDH, beta2-m and BMPC. Increased levels of TK in serum were observed in MIBI-or PET/CT-positive patients. Combination of positivity ofimaging methods which can localize active tumor lesions and increased levels of TK in serum can have an impact on decision-making and optimization of the therapeutic approach.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FD - Oncology and haematology

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Biomedical Papers-Olomouc

ISSN

1213-8118

e-ISSN

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Volume of the periodical

159

Issue of the periodical within the volume

1

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

4

Pages from-to

135-138

UT code for WoS article

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EID of the result in the Scopus database

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