Paraoxonase 2 Cys311Ser polymorphism and its association with the systolic blood pressure values in asymptomatic dyslipidemic individuals: A pilot study (Article)

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F15%3A33156561" target="_blank" >RIV/61989592:15110/15:33156561 - isvavai.cz</a>

Alternative codes found

RIV/00098892:_____/15:#0000873

Result on the web

<a href="http://dx.doi.org/10.1515/labmed-2015-0009" target="_blank" >http://dx.doi.org/10.1515/labmed-2015-0009</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1515/labmed-2015-0009" target="_blank" >10.1515/labmed-2015-0009</a>

Result language

angličtina

Original language name

Paraoxonase 2 Cys311Ser polymorphism and its association with the systolic blood pressure values in asymptomatic dyslipidemic individuals: A pilot study (Article)

Original language description

Background: The study aimed to evaluate the relationship of paraoxonase 2 (PON2) gene Cys311Ser variants with blood pressure values, endothelial/hemostatic marker levels, and other laboratory parameters in asymptomatic dyslipidemic subjects. The same analyses were also performed with the common variants of PON2 Cys311Ser and -T1131C apolipoprotein A5 (ApoA5) polymorphisms, and PON2 Cys311Ser and apolipoprotein E (ApoE) polymorphisms. Methods: Two hundred and sixty-four individuals were included in the study. The laboratory parameters were assessed by routine kit methods, while methods based on polymerase chain reaction were used for PON2, ApoA5, and ApoE genotyping. Results: PON2 311 SS homozygous individuals had significantly lower systolic blood pressure values (SBP, p<0.01), C-reactive protein, and apolipoprotein A1 levels (p<0.05), as compared with C allele carriers. The analysis revealed no differences in the levels of endothelial/hemostatic markers, except for the increased adhes

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FB - Endocrinology, diabetology, metabolism, nutrition

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Laboratory Medicine

ISSN

1439-0477

e-ISSN

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Volume of the periodical

39

Issue of the periodical within the volume

4

Country of publishing house

DE - GERMANY

Number of pages

9

Pages from-to

249-257

UT code for WoS article

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EID of the result in the Scopus database

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