Content of distinct metals in periprosthetic tissues and pseudosynovial joint fluid in patients with total joint arthroplasty
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F19%3A73597787" target="_blank" >RIV/61989592:15110/19:73597787 - isvavai.cz</a>
Alternative codes found
RIV/61989592:15310/19:73597787
Result on the web
<a href="https://onlinelibrary.wiley.com/doi/full/10.1002/jbm.b.34137" target="_blank" >https://onlinelibrary.wiley.com/doi/full/10.1002/jbm.b.34137</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/jbm.b.34137" target="_blank" >10.1002/jbm.b.34137</a>
Alternative languages
Result language
angličtina
Original language name
Content of distinct metals in periprosthetic tissues and pseudosynovial joint fluid in patients with total joint arthroplasty
Original language description
This prospective study examined the content of metals released from total joint arthroplasty into joint fluid, whole blood and periprosthetic tissues. We determined the levels of Ti, V, Nb, Co, Cr, and Mo, using inductively coupled plasma mass spectrometry, in samples from patients who underwent reoperation of total hip or knee arthroplasty. All of the patients (n = 117) included in the study had either metal on polyethylene or ceramic on polyethylene-bearing pairs. First, our results conclusively showed that the majority of released metals were deposited in periprosthetic tissues. In this context, the bloodstream turned out to be an ineffective biomarker of the effects occurring in local tissues. Second, there was a clear time-dependent nature of metallic accumulation. Based on our extensive dataset, we found significantly elevated levels of the released metals in joint fluid and periprosthetic tissues originating from loosened implants compared to stable ones, as well as recognizable differences between the groups with stable implants and aseptic loosening. Finally, it was proved that the concentrations of metals decreased dependent on the distance of the tissue from the implant.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10406 - Analytical chemistry
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS
ISSN
1552-4973
e-ISSN
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Volume of the periodical
107
Issue of the periodical within the volume
2
Country of publishing house
US - UNITED STATES
Number of pages
9
Pages from-to
454-462
UT code for WoS article
000455252200025
EID of the result in the Scopus database
2-s2.0-85044949749