Antimalarial, antiproliferative, and apoptotic activity of quinoline-chalcone and quinoline-pyrazoline hybrids. A dual action
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F19%3A73598854" target="_blank" >RIV/61989592:15110/19:73598854 - isvavai.cz</a>
Result on the web
<a href="https://link.springer.com/content/pdf/10.1007/s00044-019-02435-0.pdf" target="_blank" >https://link.springer.com/content/pdf/10.1007/s00044-019-02435-0.pdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00044-019-02435-0" target="_blank" >10.1007/s00044-019-02435-0</a>
Alternative languages
Result language
angličtina
Original language name
Antimalarial, antiproliferative, and apoptotic activity of quinoline-chalcone and quinoline-pyrazoline hybrids. A dual action
Original language description
Malaria is a multifaceted tropical disease that has been transmitted by the bite of female Anopheles mosquitoes (Plewes et al. 2019). Five species are responsible for the infection Plasmodium falciparum, vivax, ovale, malariae, and lastly Knowlesi (Plewes et al. 2019). According to the World Malaria Report (World Health Organization 2018), there is an increase in malaria cases, more than 2 million from 2016 (217 million cases) to 2017 (219 million cases), the estimated number of malaria deaths stood at 435,000 in 2017. The increase is due to the lack of proper controls in several countries (Grillet et al. 2019). It is concluded that new approaches for treatment are urgently needed. Malaria incidence can be decreased through vector control; however, resistance to insecticides and chemotherapeutics have difficulted the task (WHO 2018; Grillet et al. 2019).
Czech name
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Czech description
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Classification
Type
J<sub>SC</sub> - Article in a specialist periodical, which is included in the SCOPUS database
CEP classification
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OECD FORD branch
10608 - Biochemistry and molecular biology
Result continuities
Project
—
Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
MEDICINAL CHEMISTRY RESEARCH
ISSN
1054-2523
e-ISSN
—
Volume of the periodical
2019
Issue of the periodical within the volume
28
Country of publishing house
US - UNITED STATES
Number of pages
17
Pages from-to
2050-2066
UT code for WoS article
000489305700020
EID of the result in the Scopus database
2-s2.0-85074209326