Potential utilization of neopterin measurements in the assessment of pyrexia in metastatic melanoma treated with combined targeted therapy: a case report
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F20%3A73602834" target="_blank" >RIV/61989592:15110/20:73602834 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11160/20:10415187
Result on the web
<a href="https://www.degruyter.com/view/journals/pteridines/31/1/article-p151.xml" target="_blank" >https://www.degruyter.com/view/journals/pteridines/31/1/article-p151.xml</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1515/pteridines-2020-0009" target="_blank" >10.1515/pteridines-2020-0009</a>
Alternative languages
Result language
angličtina
Original language name
Potential utilization of neopterin measurements in the assessment of pyrexia in metastatic melanoma treated with combined targeted therapy: a case report
Original language description
In patients with metastatic melanoma the advent of targeted therapy and immune checkpoint inhibitors has transformed the management of advanced and metastatic disease, resulting in improved outcomes. Neopterin is a biomarker of immune activation increased in cancer as well as in other conditions associated with immune activation. We present a case of a patient with advanced metastatic melanoma responding to the combination targeted therapy with dabrafenib and trametinib. The treatment was complicated by a fever that was accompanied by a marked rise in serum and urinary neopterin concentrations. Present case report illustrates not only the efficacy of combined targeted therapy, but also the utilization of neopterin measurements in the diagnosis and monitoring of pyrexia in patients with metastatic malignant melanoma.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
30204 - Oncology
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
PTERIDINES
ISSN
0933-4807
e-ISSN
—
Volume of the periodical
31
Issue of the periodical within the volume
1
Country of publishing house
DE - GERMANY
Number of pages
7
Pages from-to
151-157
UT code for WoS article
000564757400001
EID of the result in the Scopus database
2-s2.0-85091665399