New aromatic 6-substituted 2 '-deoxy-9-(beta)-D-ribofuranosylpurine derivatives as potential plant growth regulators

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F20%3A73604703" target="_blank" >RIV/61989592:15110/20:73604703 - isvavai.cz</a>

Alternative codes found

RIV/61989592:15310/20:73604703

Result on the web

<a href="https://www.sciencedirect.com/science/article/pii/S0968089619317304" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0968089619317304</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.bmc.2019.115230" target="_blank" >10.1016/j.bmc.2019.115230</a>

Result language

angličtina

Original language name

New aromatic 6-substituted 2 '-deoxy-9-(beta)-D-ribofuranosylpurine derivatives as potential plant growth regulators

Original language description

Cytokinins are naturally occurring substances that act as plant growth regulators promoting plant growth and development, including shoot initiation and branching, and also affecting apical dominance and leaf senescence. Aromatic cytokinin 6-benzylaminopurine (BAP) has been widely used in micropropagation systems and biotechnology. However, its 9-glucoside (BAP9G) accumulates in explants, causing root inhibition and growth heterogenity. To overcome BAP disadvantages, a series of ring-substituted 2&apos;-deoxy-9-(beta)-D-ribofuranosylpurine derivatives was prepared and examined in different classical cytokinin bioassays. Amaranthus, senescence and tobacco callus bioassays were employed to provide details of cytokinin activity of 2&apos;-deoxy-9-(beta)-D-ribosides compared to their respective free bases and ribosides. The prepared derivatives were also tested for their recognition by cytokinin receptors of Arabidopsis thaliana AHK3 and CRE1/AHK4. The ability of aromatic N-6-substituted adenine-2&apos;-deoxy-9-(beta)-D-ribosides to promote plant growth and delay senescence was increased considerably and, in contrast to BAP, no loss of cytokinin activity at higher concentrations was observed. The presence of a 2&apos;-deoxyribosyl moiety at the N9-position led to an increase in cytokinin activities in comparison to the free bases and ribosides. The antioxidant capacity, cytotoxicity and effect on the MHV-68 gammaherpesvirus strain were also examined.

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10611 - Plant sciences, botany

Project

<a href="/en/project/EF16_019%2F0000827" target="_blank" >EF16_019/0000827: Plants as a tool for sustainable global development</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Publication year

2020

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

BIOORGANIC &amp; MEDICINAL CHEMISTRY LETTERS

ISSN

0960-894X

e-ISSN

—

Volume of the periodical

28

Issue of the periodical within the volume

2

Country of publishing house

GB - UNITED KINGDOM

Number of pages

15

Pages from-to

"115230-1"-"115230-15"

UT code for WoS article

000504647600008

EID of the result in the Scopus database

2-s2.0-85077001027