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The association of a reduced susceptibility to moxifloxacin in causative Clostridium (Clostridioides) difficile strain with the clinical outcome of patients

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F20%3A73605791" target="_blank" >RIV/61989592:15110/20:73605791 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216224:14110/20:00116176 RIV/00216208:11130/20:10412532 RIV/65269705:_____/20:00072853 RIV/00064211:_____/20:W0000021 and 6 more

  • Result on the web

    <a href="https://aricjournal.biomedcentral.com/articles/10.1186/s13756-020-00765-y#citeas" target="_blank" >https://aricjournal.biomedcentral.com/articles/10.1186/s13756-020-00765-y#citeas</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1186/s13756-020-00765-y" target="_blank" >10.1186/s13756-020-00765-y</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    The association of a reduced susceptibility to moxifloxacin in causative Clostridium (Clostridioides) difficile strain with the clinical outcome of patients

  • Original language description

    Clostridium difficile, recently reclassified as Clostridioides difficile [1], is a leading pathogen of gastrointestinal infections in hospitalised patients [2]. Between 2005 and 2013, several European multicentre studies aimed at mapping C. difficile epidemiology in Europe and an increase of CDI incidence density was found to be concomitant with changes in prevailing ribotypes; however, the design of the studies varied [3]. To standardize CDI epidemiology data collection, the European centre for disease prevention and control (ECDC) released a surveillance protocol with three options of CDI surveillance intensity (“minimal, light and enhanced”). The “minimal option” collects hospital-level CDI data, the “light version” collects also CDI case-based data, including data on mortality. The “enhanced” option collects hospital data, CDI case based data and microbiological data. Microbiological data includes results on C. difficile isolates ribotyping, the presence of toxins A/B or toxin genes and antimicrobial susceptibility testing to metronidazole, vancomycin and moxifloxacin [3]. While metronidazole and vancomycin are recommended as CDI treatment drugs [4], a reduced susceptibility to moxifloxacin a fluoroquinolone class of drug, is suggested as an epidemiological marker for certain C. difficile ribotypes spread in healthcare settings [5].

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10606 - Microbiology

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2020

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Antimicrobial Resistance and Infection Control

  • ISSN

    2047-2994

  • e-ISSN

  • Volume of the periodical

    9

  • Issue of the periodical within the volume

    98

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    7

  • Pages from-to

    "'98(1)'"-"'98(7)'"

  • UT code for WoS article

    000552013900002

  • EID of the result in the Scopus database

    2-s2.0-85087419563