Arterial Hypertension and Risk of Recurrent Event in Young Ischemic Stroke Patients
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F21%3A73608556" target="_blank" >RIV/61989592:15110/21:73608556 - isvavai.cz</a>
Alternative codes found
RIV/00098892:_____/21:N0000079
Result on the web
<a href="https://www.cambridge.org/core/journals/canadian-journal-of-neurological-sciences/article/abs/arterial-hypertension-and-risk-of-recurrent-event-in-young-ischemic-stroke-patients/89035C28C2559F258834490FB3973992" target="_blank" >https://www.cambridge.org/core/journals/canadian-journal-of-neurological-sciences/article/abs/arterial-hypertension-and-risk-of-recurrent-event-in-young-ischemic-stroke-patients/89035C28C2559F258834490FB3973992</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1017/cjn.2020.200" target="_blank" >10.1017/cjn.2020.200</a>
Alternative languages
Result language
angličtina
Original language name
Arterial Hypertension and Risk of Recurrent Event in Young Ischemic Stroke Patients
Original language description
Introduction: In young patients, the cause of ischemic stroke (IS) remains often cryptogenic despite presence of traditional vascular risk factors (VRFs). Since arterial hypertension (AH) is considered the most important one, we aimed to evaluate the impact of AH and blood pressure (BP) levels after discharge on risk of recurrent IS (RIS) in young patients. Methods: The study set consisted of acute IS patients < 50 years of age enrolled in the prospective Heart and Ischemic STrOke Relationship studY registered on ClinicalTrials.gov (NCT01541163). Cause of IS was assessed according to the ASCOD classification. Results: Out of 319 enrolled patients <50 years of age (179 males, mean age 41.1 ± 7.8 years), AH was present in 120 (37.6%) of them. No difference was found in the rates of etiological subtypes of IS between patients with and without AH. Patients with AH were older, had more VRF, used more frequently antiplatelets prior IS, and had more RIS (10 vs. 1%, p = 0.002) during a follow-up (FUP) with median of 25 months. Multivariate logistic regression stepwise model showed the prior use of antiplatelets as only predictor of RIS (p = 0.011, OR: 6.125; 95% CI: 1.510–24.837). Patients with elevated BP levels on BP Holter 1 month after discharge did not have increased rate of RIS during FUP (3.8 vs. 1.7%, p = 1.000). Conclusion: AH occurred in 37.6% of young IS patients. Patients with AH had more frequently RIS. Prior use of antiplatelets was found only predictor of RIS in young IS patients with AH.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30210 - Clinical neurology
Result continuities
Project
<a href="/en/project/NV17-30101A" target="_blank" >NV17-30101A: Risk factors of ischemic stroke in young patients and relation with epidemiologic, social and economic parameters and life style</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES
ISSN
0317-1671
e-ISSN
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Volume of the periodical
48
Issue of the periodical within the volume
3
Country of publishing house
US - UNITED STATES
Number of pages
7
Pages from-to
"358 "- 364
UT code for WoS article
000644429600009
EID of the result in the Scopus database
2-s2.0-85104968252