Multicomponent Reactions: A Promising Approach to Isotope Labeling
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F24%3A73627288" target="_blank" >RIV/61989592:15110/24:73627288 - isvavai.cz</a>
Alternative codes found
RIV/61989592:15640/24:73627288
Result on the web
<a href="https://www.thieme-connect.de/products/ejournals/html/10.1055/a-2331-6399" target="_blank" >https://www.thieme-connect.de/products/ejournals/html/10.1055/a-2331-6399</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1055/a-2331-6399" target="_blank" >10.1055/a-2331-6399</a>
Alternative languages
Result language
angličtina
Original language name
Multicomponent Reactions: A Promising Approach to Isotope Labeling
Original language description
Isotopic labeling is an attractive modality that has been widely used in many aspects of chemistry, the life sciences, and medical research; especially deuterated drugs and radioactive molecules have been used in the diagnosis and treatment of cancer and neurodegenerative diseases. The widespread application and rapid development of isotopically labeled molecules has led to an increased demand for new isotopic labeling chemical methods to synthesize highly specific molecules bearing defined nuclides. Multicomponent reactions (MCRs) are modular build-up approaches for the rapid generation of complex molecules often containing biologically relevant scaffold structures. There is great potential to use MCRs to construct isotopically labeled molecules because assembly speed and reaction diversity are key advantages of MCR. In this review, we provide an overview of the recent literature on this topic that can provide insight into the application of MCRs in the field of isotopic labeling.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10401 - Organic chemistry
Result continuities
Project
<a href="/en/project/LX22NPO5102" target="_blank" >LX22NPO5102: National institute for cancer research</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
SYNLETT
ISSN
0936-5214
e-ISSN
1437-2096
Volume of the periodical
35
Issue of the periodical within the volume
19
Country of publishing house
DE - GERMANY
Number of pages
17
Pages from-to
2174-2190
UT code for WoS article
001315382800003
EID of the result in the Scopus database
2-s2.0-85204740847