Magnetic 2D Transition-Metal-Based Nanomaterials in Biomedicine: Opportunities and Challenges in Cancer Therapy

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F25%3A73631231" target="_blank" >RIV/61989592:15110/25:73631231 - isvavai.cz</a>

Alternative codes found

RIV/61989592:15640/25:73631231

Result on the web

<a href="https://www.mdpi.com/1996-1944/18/11/2570" target="_blank" >https://www.mdpi.com/1996-1944/18/11/2570</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/ma18112570" target="_blank" >10.3390/ma18112570</a>

Result language

angličtina

Original language name

Magnetic 2D Transition-Metal-Based Nanomaterials in Biomedicine: Opportunities and Challenges in Cancer Therapy

Original language description

Severe systemic toxicity and poor targeting efficiency remain major limitations of traditional chemotherapy, emphasising the need for smarter drug delivery systems. Magnetic 2D transition-metal-based nanomaterials offer a promising approach, as they can be designed to combine high drug loading, precise targeting, and controlled release. The key material classes—transition metal dichalcogenides, transition metal carbides/nitrides, transition metal oxides, and metal–organic frameworks—share important physicochemical properties. These include high surface-to-volume ratios, tuneable functionalities, and efficient intracellular uptake. Incorporating magnetic nanoparticles into these 2D structures broadens their potential beyond drug delivery, through enabling multimodal therapeutic strategies such as hyperthermia induction, real-time imaging, and photothermal or photodynamic therapy. This review outlines the potential of magnetic 2D transition-metal-based nanomaterials for biomedical applications by evaluating their therapeutic performance and biological response. In parallel, it offers a critical analysis of how differences in physicochemical properties influence their potential for specific cancer treatment applications, highlighting the most promising uses of each in bionanomedicine.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10608 - Biochemistry and molecular biology

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2025

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Materials

ISSN

1996-1944

e-ISSN

—

Volume of the periodical

18

Issue of the periodical within the volume

11

Country of publishing house

CH - SWITZERLAND

Number of pages

28

Pages from-to

2570

UT code for WoS article

001505978000001

EID of the result in the Scopus database

2-s2.0-105007850468