Promoting Medical Innovation
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15260%2F17%3A73584087" target="_blank" >RIV/61989592:15260/17:73584087 - isvavai.cz</a>
Result on the web
<a href="https://obd.upol.cz/id_publ/333163972" target="_blank" >https://obd.upol.cz/id_publ/333163972</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1377/hlthaff.2017.0803" target="_blank" >10.1377/hlthaff.2017.0803</a>
Alternative languages
Result language
angličtina
Original language name
Promoting Medical Innovation
Original language description
In developed countries, governments and not-for-profit organizations invest heavily in biomedical research and drug development. Paradoxically, when scientists from Bayer Healthcare analyzed sixtyseven laboratory research projects, forty-seven of which were in the field of oncology, they found that only 25 percent of the projects had completely reproducible results. In another study, researchers from Amgen confirmed the results of only six of fifty-three landmark studies in the field of preclinical oncology or hematology. Recently, it was estimatedthat the cumulative prevalence of irreproducible results in preclinical research in general exceeds 50 percent and costs roughly $28 billion per year in the United States alone. I suggest that there is a need to raise awareness of these problems among physicians and to demand more resources for nonprofit funding of clinical trials of unpatentable drugs instead of irreproducible preclinical research.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30304 - Public and environmental health
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Health Affairs
ISSN
0278-2715
e-ISSN
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Volume of the periodical
36
Issue of the periodical within the volume
8
Country of publishing house
US - UNITED STATES
Number of pages
1
Pages from-to
1518
UT code for WoS article
000407080200028
EID of the result in the Scopus database
2-s2.0-85027166929