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Cytokinins in biotechnology and medicine

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F03%3A00001597" target="_blank" >RIV/61989592:15310/03:00001597 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Cytokinins in biotechnology and medicine

  • Original language description

    New series of cytokinins derived from 6-benzylaminopurine (BAP) have been developed for agricultural and biotechnological applications. These compounds exhibit very high biological activities in different cytokinin bioassays. Preferentially, the methoxyand fluoro derivatives had 2-10 times higher activity then trans-zeatin and expressed very positive antisenescent and morphogenetic properties in different in vitro cultures of some horticulture species. These compounds have been recently identified as new natural cytokinins. Our research focused on the primary mechanism of action of plant hormones cytokinins in cell division cycle has showed that natural plant cytokinins are rather non-specific inhibitors of various protein kinases. Surprisingly, amongaromatic cytokinin derivatives, we have discovered a compound, 2-(2-hydroxyethylamino)-6-benzylamino-9-methylpurine, named "olomoucine", which specifically inhibits some cyclin-dependent kinases (cdks) at micromolar concentration. One of

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    ED - Physiology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GA522%2F03%2F0323" target="_blank" >GA522/03/0323: Investigation of algae and cyanobacteria as producers of biologically active substances</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2003

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    2nd Symposium of the Croatian Society on Plant Physiology

  • ISBN

  • ISSN

  • e-ISSN

  • Number of pages

    200

  • Pages from-to

    168

  • Publisher name

    Coratian Biological Society

  • Place of publication

    Zagreb

  • Event location

    Zagreb

  • Event date

  • Type of event by nationality

    WRD - Celosvětová akce

  • UT code for WoS article