Synthesis, NMR spectra and X-ray data of chloro and dichloro derivatives of 3-hydroxy-2-phenylquinolin-4(1H)-ones and their cytostatic activity

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F04%3A00002406" target="_blank" >RIV/61989592:15310/04:00002406 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Synthesis, NMR spectra and X-ray data of chloro and dichloro derivatives of 3-hydroxy-2-phenylquinolin-4(1H)-ones and their cytostatic activity
Original language description
As known, some derivatives of quinolin-4(1H)-one possess interesting biological properties. The biological and cytostactic activity of the 2-substituted 3-hydroxyquinolin-4(1H)-ones has not been reported yet. In this paper the synthesis of a series of chloro and dichloro 2-phenyl-3-hydroxyquinolin-4(1H)-ones and their characterization by NMR spectra and X-ray data is described. Their cytostatic properties have been evaluated and the results are reported
Czech name
Syntéza, NMR spektra a RTG data chloro a dichloro derivátu 3-hydroxy-2-phenylchinolin-4(1H)-onu a jejich cytostatická aktivita
Czech description
Článek je věnován syntéze, NMR spektrům a RTG datům chloro a dichloro derivátu 3-hydroxy-2-phenylchinolin-4(1H)-onu a zkoumá jejich cytostatickou aktivitu.

Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CC - Organic chemistry
OECD FORD branch
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Project
<a href="/en/project/GA203%2F01%2F1360" target="_blank" >GA203/01/1360: Synthesis and biological activity of 2-aryl-3hydroxyquinolin-4(1H)-ones derivatives</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2004
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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