Using of S-(-)-2-hydroxymethyl-1,1-dimethylpyrrolidinium tetrafluoroborate as additive to the background electrolyte in capillary electrophoresis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F06%3A00003043" target="_blank" >RIV/61989592:15310/06:00003043 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Using of S-(-)-2-hydroxymethyl-1,1-dimethylpyrrolidinium tetrafluoroborate as additive to the background electrolyte in capillary electrophoresis
Original language description
We synthesised and used new type of quaternary ammonium salt [S-(-)-2-hydroxymethyl-1,1-dimethylpyrrolidinium tetrafluoroborate] as effective additive to acidic background electrolytes. We used this quaternary ammonium salt as effective agent for capillary zone electrophoresis separation of model mixture of five tricyclic antidepressants (amitriptyline, nortriptyline, imipramine, desipramine and clomipramine) as model analytes. We observed that addition of S-(-)-2-hydroxymethyl-1,1-dimethylpyrrolidiniumtetrafluoroborate ([HMDP](+) [BF4](-)) to acidic background electrolytes leads to suppression of magnitude of electroosmotic flow (EOF) and gradually change the direction of the EOF. Baseline separation of five TAs was achieved by using of 91.1 mmol L-1(20 g L-1) of [HMDP](+) [BF4](-) in 25 mmol L-1 sodium phosphate pH 2.5, where electroosmotic mobility was -11.3 x 10(-9) m(2) V-1 s(-1). We achieved baseline separation of five TAs with using of [HMDP](+) [BF4](-) as water solution too.
Czech name
Použití S-(-)-2-hydroxymethyl-1,1-dimethylpyrrolidinium tetrafluoroborátu jako aditiva do základního elektyrolytu v kapilární elektroforéza
Czech description
Syntetÿzovali jsme a použili nový typ kvartérní amoniové soli S-(-)-2-hydroxymethyl-1,1-dimethylpyrrolidinium tetrafluoroborátu jako efektivního aditiva do kyselého základního elektrolytu. Toto aditivum jsem použili pro separaci modelové směsi pětitricyklických antideprasiv. Bylo pozorováno, že přídavek S-(-)-2-hydroxymethyl-1,1-dimethylpyrrolidinium tetrafluoroborátu do základního elektrolytu vede ke snížení elektroosmotického toku a graduální změně ve směru elektroosmotického toku.
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CB - Analytical chemistry, separation
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GA203%2F03%2F0161" target="_blank" >GA203/03/0161: New progress in chiral separations</a><br>
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2006
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Chromatography
ISSN
0021-9673
e-ISSN
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Volume of the periodical
1103
Issue of the periodical within the volume
2
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
7
Pages from-to
337-343
UT code for WoS article
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EID of the result in the Scopus database
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