Colon tissue concentrations of copper, iron, selenium, and zinc in colorectal carcinoma patients

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F06%3A00003352" target="_blank" >RIV/61989592:15310/06:00003352 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Colon tissue concentrations of copper, iron, selenium, and zinc in colorectal carcinoma patients

Original language description

Concentration of four trace elements (copper, zinc, iron, and selenium) was determined in colon tissue from twenty-three patients with colorectal cancer. The tissue samples were dried and dissolved using microwave-assisted digestion technique. The content of trace elements was determined using atomic absorption spectrometry. No significant differences between Zn levels in normal and cancerous tissues were observed. However, the levels of Cu, Fe, and Se were significantly higher in cancerous tissues thanin the control samples. The results obtained using microwave-assisted technique were compared to those obtained via alkaline digestion with tetramethylammonium hydroxide. Both techniques were used for the digestion of certified reference material of pork liver. Very good agreement with the certified values of Cu, Fe, and Zn in the reference material was achieved using alkaline digestion procedure. This technique seems to be an efficient alternative to decomposition of biological samples

Czech name

Koncentrace mědi, železa, selenu a zinku v tkání střeva u pacientů s kolorektálním karcinomem

Czech description

Koncentrace 4 stopových prvků (Cu, Zn, Fe a Se) byly stanoveny ve tkáni střev od 23 pacientů s kolorektálním karcinomem. Vzorky tkání byly vysušeny a mineralizovány s využitím mikrovlnné mineralizace. Obsah stopových prvků byl stanoven s využitím AAS. Nebyly zaznamenány rozdíly mezi hladinami Zn u nádorové a kontrolní tkáně. Zatímco hladiny Cu, Fe a Se byly statisticky významně zvýšeny v nádorové tkáni.

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CB - Analytical chemistry, separation

OECD FORD branch

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Project

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Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2006

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Chemical Papers

ISSN

0366-6352

e-ISSN

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Volume of the periodical

60

Issue of the periodical within the volume

4

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

5

Pages from-to

297-301

UT code for WoS article

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EID of the result in the Scopus database

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