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Requirement of B2-type Cyclin-Dependent Kinases for meristem integrity in Arabidopsis thaliana

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F08%3A00005514" target="_blank" >RIV/61989592:15310/08:00005514 - isvavai.cz</a>

  • Alternative codes found

    RIV/61389030:_____/08:00322261

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Requirement of B2-type Cyclin-Dependent Kinases for meristem integrity in Arabidopsis thaliana

  • Original language description

    To maintain proper meristem function, cell division and differentiation must be coordinately regulated in distinct subdomains of the meristem. Although a number of regulators necessary for the correct organization of the shoot apical meristem (SAM) havebeen identified, it is still largely unknown how their function is integrated with the cell cycle machinery to translate domain identity into correct cellular behavior. We show here that the cyclin-dependent kinases CDKB2;1 and CDKB2;2 are required bothfor normal cell cycle progression and for meristem organization. Consistently, the CDKB2 genes are highly expressed in the SAM in a cell cycle-dependent fashion, and disruption of CDKB2 function leads to severe meristematic defects. In addition, strong alterations in hormone signaling both at the level of active hormones and with respect to transcriptional and physiological outputs were observed in plants with disturbed CDKB2 activity.

  • Czech name

    Potřeba cyklin-dependentních kináz B2-typů pro integritu meristému v Arabidopsis thaliana

  • Czech description

    Ukázalo se, že cyklin-dependentní kinázy CDKB2;1 a CDKB2;2 jsou potřebné pro normální průběh buněčného cyklu a pro uspořádání meristému. CDKB2 geny jsou vysoce exprimovány v nadzemním apikálním meristému (SAM) a přerušení funkce CDKB2 vede k těžkým meristematickým defektům. Navíc, silné změny v hormonálním signalingu byly pozorovány v rostlinách s narušenou CDKB2 aktivitou na úrovni aktivních hormonů a s ohledem na transkripční i fyziologické výstupy.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EF - Botany

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2008

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Plant Cell

  • ISSN

    1040-4651

  • e-ISSN

  • Volume of the periodical

    20

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    13

  • Pages from-to

  • UT code for WoS article

  • EID of the result in the Scopus database