Analysis of chiral compounds using mass spectrometric approaches
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F09%3A00010511" target="_blank" >RIV/61989592:15310/09:00010511 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Analysis of chiral compounds using mass spectrometric approaches
Original language description
Analysis of isomers is an important task of analytical chemistry. An unquestionable number of enzymes, factors, cofactors and also other biologically important compounds are isomeric. One of the most interesting groups of isomers is the group of opticalisomers. Chiral analysis is generally based on applications of separation techniques or less commonly; it is based on spectroscopic approaches. Mass spectrometry can be labeled as an interesting alternative. Several mass spectrometric methods that are able to handle enantiomeric discriminations were developed, but most of them have only one of the potentially strong approaches. This method is based on a formation of trimer diastereoisomers that are composed of analyte (one ligand), reference (2 ligands), and all three ligands are coordinated by selected bivalent metal. These trimeric clusters are generated in the ion source (usually electrospray, but nano-electrospray or DESI can be used as well). Essentially, clusters can dissociate us
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
CB - Analytical chemistry, separation
OECD FORD branch
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Result continuities
Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2009
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů