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Aminoaldehydes: reactive products of polyamine degradation

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F09%3A00010913" target="_blank" >RIV/61989592:15310/09:00010913 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Aminoaldehydes: reactive products of polyamine degradation

  • Original language description

    The oxidative degradation of diamines and polyamines catalyzed by amine oxidases produces ?-aminoaldehydes and hydrogen peroxide. ?-Aminoaldehydes may also be produced from their precursors nonoxidatively by a pyridoxal-phosphate dependent aminotransferase reaction. 3-Aminopropionaldehyde and 4-aminobutyraldehyde belong to the best substrates of NAD(P)+-dependent aminoaldehyde dehydrogenase. In this way they are oxidized to ?-alanine and 4-aminobutyric acid. 4-Aminobutyraldehyde and 5-aminovaleraldehydespontaneously cyclize to 1-pyrroline and 1-piperideine, respectively. The heterocycles are subsequently utilized in the production of several types of alkaloids. 4-Aminobutyraldehyde has recently been identified as the precursor of another kind of secondary metabolite, 2-acetyl-1-pyrroline, causing fragrance in certain rice varieties. 3-Aminopropionaldehyde is known as a potent cytotoxin. It is associated with certain diseases like cerebral ischemia and stroke.

  • Czech name

  • Czech description

Classification

  • Type

    C - Chapter in a specialist book

  • CEP classification

    CE - Biochemistry

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GA522%2F08%2F0555" target="_blank" >GA522/08/0555: Structure-functional characterization of oxidoreductases acting on nitrogenous regulatory compounds in plants</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2009

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Book/collection name

    Biologically Active Amines and Related Enzymes? Biochemical, Physiological and Clinical Aspects (Toninello A., ed.)

  • ISBN

    978-81-7895-433-2

  • Number of pages of the result

    24

  • Pages from-to

  • Number of pages of the book

    300

  • Publisher name

    Research Signpost, Transworld Research Network

  • Place of publication

    Kerala, India

  • UT code for WoS chapter