Is there a declining trend in ovarian function among infertility clinic patients?

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F10%3A10212418" target="_blank" >RIV/61989592:15310/10:10212418 - isvavai.cz</a>

Alternative codes found

RIV/68081766:_____/10:00337970

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Is there a declining trend in ovarian function among infertility clinic patients?

Original language description

Background: There is a growing body of evidence that testicular function has decreased rapidly over the last 50 years. However, much less is known about corresponding trends in ovarian function. Herein, we examine the temporal changes in ovarian functionin a large sample of infertile patients from the Czech Republic over a period of 14 years. Methods: In a retrospective study, we analysed a large body of data from women, 20?40 years of age, undergoing IVF/ICSI treatment between 1995 and 2008. We defined ovarian function using five variables: basal FSH level, estradiol (E2) level on the day of HCG administration, dose of gonadotrophins used for ovarian stimulation, number of retrieved oocytes and dose of gonadotrophins per oocyte. Controlling simultaneously for temporal changes in patient age and stimulation protocol, we applied generalized additive models to describe the temporal trends. Results: During the study period the mean age of the study population increased by 2.7 years.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FK - Gynaecology and obstetrics

OECD FORD branch

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Project

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Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach

Publication year

2010

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Human Reproduction

ISSN

0268-1161

e-ISSN

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Volume of the periodical

25

Issue of the periodical within the volume

1

Country of publishing house

GB - UNITED KINGDOM

Number of pages

6

Pages from-to

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UT code for WoS article

000272929600019

EID of the result in the Scopus database

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