THE SAFETY AND EFFICACY OF A SILYMARIN AND SELENIUM COMBINATION IN MEN AFTER RADICAL PROSTATECTOMY A SIX MONTH PLACEBO-CONTROLLED DOUBLE-BLIND CLINICAL TRIAL

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F10%3A10212887" target="_blank" >RIV/61989592:15310/10:10212887 - isvavai.cz</a>

Alternative codes found

RIV/61989592:15110/10:10212887

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

THE SAFETY AND EFFICACY OF A SILYMARIN AND SELENIUM COMBINATION IN MEN AFTER RADICAL PROSTATECTOMY A SIX MONTH PLACEBO-CONTROLLED DOUBLE-BLIND CLINICAL TRIAL

Original language description

Silymarin has anti-proliferative and anti-angiogenic activities in-xenografts of human prostate cancer (PCa). Low dietary selenium on the other hand has been associated with increased-incidence of PCa. The purpose of the current trial was to determine whether a daily administration of a silymarin and-selenium (SM-Se) combination for 6 months would alter basic clinical chemistry and oxidative stress markers, and-improve the quality of life score (QoL) in men after radical prostatectomy (RP). The selectedcombination of silymarin and selenium significantly reduced two markers of lipid metabolism-known to be associated with PCa progression, LDL and total cholesterol in the blood of men after RP. This-suggests that this combination may be effective in reducing PCa progression.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FJ - Surgery including transplantology

OECD FORD branch

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Project

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Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2010

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Biomedical Papers

ISSN

1213-8118

e-ISSN

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Volume of the periodical

2010

Issue of the periodical within the volume

3

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

6

Pages from-to

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UT code for WoS article

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EID of the result in the Scopus database

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