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Use of selenium-silymarin mix reduces lower urinary tract symptoms and prostate specific antigen in men

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F13%3A33144114" target="_blank" >RIV/61989592:15310/13:33144114 - isvavai.cz</a>

  • Alternative codes found

    RIV/61989592:15110/13:33144114 RIV/00098892:_____/13:#0000494

  • Result on the web

    <a href="http://www.phytomedicinejournal.com/article/S0944-7113(13)00281-X/abstract" target="_blank" >http://www.phytomedicinejournal.com/article/S0944-7113(13)00281-X/abstract</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.phymed.2013.07.018" target="_blank" >10.1016/j.phymed.2013.07.018</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Use of selenium-silymarin mix reduces lower urinary tract symptoms and prostate specific antigen in men

  • Original language description

    The aim of this double-blind, placebo controlled clinical trial was to assess the effects of a combination of selenium and silymarin in men with lower urinary tract symptoms, benign prostatic hyperplasia and a prostate specific antigen (PSA) ?2.5ng/ml. The volunteers were randomized to two groups: the first one (n=26) received 240?g selenium (in the form of yeast l-selenomethionine) plus 570mg silymarin daily for 6 months and the second (n=29) received placebo. Outcome measures were changes in the International Prostate Symptom Score (IPSS), bladder volume (V), urinary flow rate, ultrasound estimated postvoid residual urine volume (RV), serum PSA, testosterone and selenium levels, safety clinical biochemistry, hematology and oxidative stress parametersat baseline and on day 180. The results showed statistically significant differences (p{0.05) between treatment and control groups for the following parameters: IPSS score, urodynamic parameters: maximal rate of urine flow (Qmax), averag

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CE - Biochemistry

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2013

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Phytomedicine

  • ISSN

    0944-7113

  • e-ISSN

  • Volume of the periodical

    21

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    DE - GERMANY

  • Number of pages

    7

  • Pages from-to

    75-81

  • UT code for WoS article

  • EID of the result in the Scopus database