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The photodynamic effect: the comparison of chemiexcitation by luminol and phthalhydrazide

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F11%3A33119786" target="_blank" >RIV/61989592:15310/11:33119786 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1002/bio.1245" target="_blank" >http://dx.doi.org/10.1002/bio.1245</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1002/bio.1245" target="_blank" >10.1002/bio.1245</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    The photodynamic effect: the comparison of chemiexcitation by luminol and phthalhydrazide

  • Original language description

    The presence of light, oxygen and photosensitizer (organic dye) is required for the photodynamic effect. Light and photosensitizer are harmless by themselves, butwhen combinedwith oxygen, reactive oxygen species (ROS) can be produced. This photodynamic effect is used in photodynamic therapy (PDT); the production of ROS as lethal cytotoxic agents can inactivate tumor cells. However, during PDT, there aremany difficulties, so it is not possible to excite the photosensitizer using a laser, a source of light at the wavelengths specific to the photosensitizer (in visible region of the spectrum). Chemiluminescence is the light emission as a result of a chemical reaction. It is possible to use a chemiluminescent mixture to excite the photosensitizer even if the light emission does not conform to the absorption maximum of the photosensitizer. Luciferin and luminol have been used as chemiluminescent compounds (energizers) for the excitation of the photosensitizers.The aimof this workwas to comp

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CF - Physical chemistry and theoretical chemistry

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2011

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Luminescence

  • ISSN

    1522-7235

  • e-ISSN

  • Volume of the periodical

    26

  • Issue of the periodical within the volume

    6

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    6

  • Pages from-to

    410-415

  • UT code for WoS article

    000297923800005

  • EID of the result in the Scopus database