Plant Aurora kinases play a role in maintenance of primary meristems and control of endoreduplication
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F12%3A33140799" target="_blank" >RIV/61989592:15310/12:33140799 - isvavai.cz</a>
Alternative codes found
RIV/61388971:_____/12:00380510 RIV/61389030:_____/12:00380510
Result on the web
<a href="http://onlinelibrary.wiley.com/doi/10.1111/j.1469-8137.2011.03989.x/pdf" target="_blank" >http://onlinelibrary.wiley.com/doi/10.1111/j.1469-8137.2011.03989.x/pdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/j.1469-8137.2011.03989.x" target="_blank" >10.1111/j.1469-8137.2011.03989.x</a>
Alternative languages
Result language
angličtina
Original language name
Plant Aurora kinases play a role in maintenance of primary meristems and control of endoreduplication
Original language description
The conserved family of Aurora kinases has multiple functions during mitosis. The roles of plant Aurora kinases have been characterized using inhibitor treatments. We down-regulated Aurora kinases in Arabidopsis thaliana using RNA interference (RNAi). Wecarried out a detailed phenotypic analysis of Aurora RNAi plants, biochemical and microscopic studies of AtAurora1 kinase together with AtTPX2 (targeting protein for Xklp2) and ?-tubulin. Cell division defects were observed in plants with reduced expression of Aurora kinases. Furthermore, the maintenance of primary meristems was compromised and RNAi seedlings entered endoreduplication prematurely. AtAurora1, its activator AtTPX2, and ?-tubulin were associated with microtubules in vitro; they were attached to regrowing kinetochore microtubules and colocalized on spindle microtubules and with a subset of early phragmoplast microtubules. Only the AtAurora1 kinase was translocated to the area of the cell plate. RNAi silencing of Aurora kin
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CE - Biochemistry
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
New Phytologist (print)
ISSN
0028-646X
e-ISSN
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Volume of the periodical
193
Issue of the periodical within the volume
3
Country of publishing house
GB - UNITED KINGDOM
Number of pages
15
Pages from-to
590-604
UT code for WoS article
000298984900006
EID of the result in the Scopus database
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