SOD-Mimic Cu(II) Dimeric Complexes Involving Kinetin and Its Derivative: Preparation and Characterization
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F12%3A33140830" target="_blank" >RIV/61989592:15310/12:33140830 - isvavai.cz</a>
Result on the web
<a href="http://www.hindawi.com/journals/bca/2012/704329/cta/" target="_blank" >http://www.hindawi.com/journals/bca/2012/704329/cta/</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1155/2012/704329" target="_blank" >10.1155/2012/704329</a>
Alternative languages
Result language
angličtina
Original language name
SOD-Mimic Cu(II) Dimeric Complexes Involving Kinetin and Its Derivative: Preparation and Characterization
Original language description
Two SOD-mimic active dimeric Cu(II) chlorido complexes of the compositions [Cu2(HL1)(4)Cl2]Cl2 (1) and [Cu2(HL2)(2)(Cl)(2)(HL2)(2)Cl2].4H2O (2) involving the cosmetologically relevant cytokinin kinetin (N6-furfuryladenine, HL1) and its derivative N6-(5-methylfurfuryl) adenine (HL2) have been synthesized and characterized by elemental analysis, infrared, and electronic spectroscopy, ESI+ mass spectrometry, conductivity and temperature dependence of magnetic susceptibility measurements, and thermogravimetric (TG) and differential thermal (DTA) analyses. The results of these methods, particularly the temperature dependence of magnetic susceptibility, showed the complexes to be dimeric with a strong antiferromagnetic exchange (J = -290 cm(-1) for complex 1and J = -160 cm(-1) for 2). The complexes have been identified as auspicious SOD-mimics, as their antiradical activity evaluated by the in vitro SOD-mimic assay resulted in the IC50 values equal to 8.13 uM (1) and 0.71 uM (2).
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CA - Inorganic chemistry
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Bioinorganic Chemistry and Applications
ISSN
1565-3633
e-ISSN
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Volume of the periodical
2012
Issue of the periodical within the volume
JUL
Country of publishing house
US - UNITED STATES
Number of pages
8
Pages from-to
704329
UT code for WoS article
000308501100001
EID of the result in the Scopus database
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