Incidence of potential drug interactions in medication prescriptions for children and adolescents in the University Hospital Olomouc, Czech Republic

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F13%3A33141632" target="_blank" >RIV/61989592:15310/13:33141632 - isvavai.cz</a>

Alternative codes found

RIV/00098892:_____/13:#0000607

Result on the web

<a href="http://dx.doi.org/10.1007/s00431-013-1933-7" target="_blank" >http://dx.doi.org/10.1007/s00431-013-1933-7</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00431-013-1933-7" target="_blank" >10.1007/s00431-013-1933-7</a>

Result language

angličtina

Original language name

Incidence of potential drug interactions in medication prescriptions for children and adolescents in the University Hospital Olomouc, Czech Republic

Original language description

Drug interactions are important potential causes of adverse drug reactions. However, studies of their occurrence in children are almost entirely lacking. This study evaluates the incidence of potential drug interactions (PDIs) in medication prescriptionsfor children. The study was performed at the University Hospital in Olomouc. PDIs in each patient's prescriptions were identified. Multivariate analysis was performed in order to assess the risk factors confounding the potential interactions. Univariateanalysis was used to assess which diagnostic groups and medication groups significantly increase or lower the odds of a potential drug?drug interaction. A total of 6,078 patients meeting the inclusion criteria entered the study. They received 19,522 prescriptions. PDIs were identified in 3.83 % of patients (moderate-to-severe cases in 0.47 %). Patient age (p=0.008), the average number of prescriptions per visit (p{0.0001), and the number of visits per year (p{0.0001) were found to incre

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FR - Pharmacology and apothecary chemistry

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

European Journal of Pediatrics

ISSN

0340-6199

e-ISSN

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Volume of the periodical

172

Issue of the periodical within the volume

5

Country of publishing house

DE - GERMANY

Number of pages

8

Pages from-to

631-638

UT code for WoS article

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EID of the result in the Scopus database

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