Structural and functional characterization of a plant S-nitrosoglutathione reductase from Solanum lycopersicum

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F13%3A33147734" target="_blank" >RIV/61989592:15310/13:33147734 - isvavai.cz</a>

Result on the web

<a href="http://www.sciencedirect.com/science/article/pii/S0300908412004877" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0300908412004877</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.biochi.2012.12.009" target="_blank" >10.1016/j.biochi.2012.12.009</a>

Result language

angličtina

Original language name

Structural and functional characterization of a plant S-nitrosoglutathione reductase from Solanum lycopersicum

Original language description

S-nitrosoglutathione reductase (GSNOR), also known as S-(hydroxymethyl)glutathione (HMGSH) dehydrogenase, belongs to the alcohol dehydrogenase superfamily, namely to the class III ADHs. GSNOR catalyses the oxidation of HMGSH to S-formylglutathione usinga catalytic zinc and NAD(+) as a coenzyme. The enzyme also catalyses the NADH-dependent reduction of S-nitrosoglutathione (GSNO). In plants, GSNO has been suggested to serve as a nitric oxide (NO) reservoir locally or possibly as NO donor in distant cells and tissues. NO and NO-related molecules such as S-nitrosothiols (S-NOs) play a central role in the regulation of normal plant physiological processes and host defence. The enzyme thus participates in the cellular homeostasis of S-NOs and in the metabolism of reactive nitrogen species. Although GSNOR has recently been characterized from several organisms, this study represents the first detailed biochemical and structural characterization of a plant GSNOR, that from tomato (Solanum lyc

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CE - Biochemistry

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Biochimie

ISSN

0300-9084

e-ISSN

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Volume of the periodical

95

Issue of the periodical within the volume

4

Country of publishing house

FR - FRANCE

Number of pages

14

Pages from-to

889-902

UT code for WoS article

000316513100030

EID of the result in the Scopus database

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