Parasitic fungus Claviceps as a source for biotechnological production of ergot alkaloids

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F13%3A33147803" target="_blank" >RIV/61989592:15310/13:33147803 - isvavai.cz</a>

Result on the web

<a href="http://www.sciencedirect.com/science/article/pii/S0734975012000079" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0734975012000079</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.biotechadv.2012.01.005" target="_blank" >10.1016/j.biotechadv.2012.01.005</a>

Result language

angličtina

Original language name

Parasitic fungus Claviceps as a source for biotechnological production of ergot alkaloids

Original language description

Ergot alkaloids produced by the fungus Claviceps parasitizing on cereals, include three major groups: clavine alkaloids, D-lysergic acid and its derivatives and ergopeptines. These alkaloids are important substances for the pharmatech industry, where they are used for production of anti-migraine drugs, uterotonics, prolactin inhibitors, anti-Parkinson agents, etc. Production of ergot alkaloids is based either on traditional field cultivation of ergot-infected rye or on submerged cultures of the fungus in industrial fermentation plants. In 2010, the total production of these alkaloids in the world was about 20,000 kg, of which field cultivation contributed about 50%. This review covers the recent advances in understanding of the genetics and regulationof biosynthesis of ergot alkaloids, focusing on possible applications of the new knowledge to improve the production yield.

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EE - Microbiology, virology

OECD FORD branch

—

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Biotechnology Advances

ISSN

0734-9750

e-ISSN

—

Volume of the periodical

31

Issue of the periodical within the volume

1 - SI

Country of publishing house

US - UNITED STATES

Number of pages

10

Pages from-to

79-89

UT code for WoS article

000315761200008

EID of the result in the Scopus database

—